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almotriptan (AXERT)

Drug and Dietary Supplement Profiles

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Disease and Drug Family Information

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  • Migraine Headaches [hide all summaries]
    For reasons of both safety and cost, the newer migraine drugs known as triptans should be used only after determining that the NSAIDs and acetaminophen fail to work. The triptans can dangerously, even fatally, narrow arteries in the heart.

Worst Pills, Best Pills Newsletter Articles

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  • Updates: Migraine, Depression, Hypertension Drugs [hide all summaries]
    (December 2012)
    Topics discussed include evidence that overuse of migraine drugs may cause headache rather than relieve it. Also, a widely prescribed antidepressant, in higher doses, can cause heart arrhythmias, manifested as dizziness, palpitations or fainting. Finally, another widely used antidepressant can cause a life-threatening condition called neuroleptic malignant syndrome, which can include extremely high body temperature, fast heart rate, rapidly changing blood pressure and mental changes.
  • Serotonin Syndrome Due to Drug Interactions [hide all summaries]
    (April 2008)
    The article lists more than 30 prescription drugs that can cause the serotonin syndrome.
  • PUBLIC HEALTH ADVISORY: Migraine Drugs, Antidepressants May Cause Life-Threatening Interactions [hide all summaries]
    (October 2006)
    If you are taking triptans, SSRIs or SNRIs and experience the symptoms of serotonin syndrome listed in this article, you should seek medical attention immediately. This is because of the possibility of life-threatening reactions such as nausea, changes in blood pressure or hallucinations that may be caused by the interaction of migraine headache drugs, called triptans, and certain antidepressants.

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