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diltiazem (CARDIZEM, CARDIZEM CD, CARDIZEM LA, CARTIA XT, DILACOR XR, DILT-CD, DITZAC, TAZTIA, TIAZAC)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion

Disease and Drug Family Information

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • High Blood Pressure [hide all summaries]
    A study of nutritional therapy showed that over one-third of people who previously needed drug treatment for high blood pressure were able to adequately control their blood pressure with nutritional therapy alone.Several factors should be taken into account when considering whether your high blood pressure should be treated. One is the benefits of the treatment for your blood pressure, which vary significantly depending on how high it is, your age, and whether you have other risk factors such as high cholesterol or are a smoker or a diabetic, and whether you have had a heart attack, heart failure, a stroke, or have kidney damage. The other consideration is the risks or the adverse effects of the treatment, which will vary depending on what is being considered.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Drugs That Cause Sun-Related Skin Reactions [hide all summaries]
    (July 2016)
    Summer is a terrific time for healthy outdoor activities, such as walking, hiking, biking and swim¬ming. But for an unlucky few, certain medications can lead to adverse skin reactions following exposure to the sun. Find out whether you are at risk and how to protect yourself.
  • With Some Drugs, Crushing Tablets Or Opening Capsules Could Have Fatal Consequences [hide all summaries]
    (February 2015)
    Patients who have difficulty swallowing pills will sometimes crush tablets or open capsules and sprinkle the resulting powder, fragments or granules into food or liquids. Other patients will resort to chewing their pills before swallowing. Find out the dangers posed by taking such measures.
  • New Atrial Fibrillation Treatment Guidelines Released [hide all summaries]
    (August 2014)
    Atrial fibrillation is one of the most common heart rhythm disorders, afflicting more than 2.7 million Americans. Learn about the most recent guidelines for treating this disorder, issued by the American College of Cardiology and the American Heart Association, and about Public Citizen’s Health Research Group’s assessment of those guidelines.
  • Update on Grapefruit Juice-Drug Interactions [hide all summaries]
    (July 2012)
    This article updates and expands our earlier list of drugs that can have harmful interactions with grapefruit juice. The list now includes 82 different drugs.
  • Some Anti-Hypertensive Drugs Increase the Risk of Gout [hide all summaries]
    (May 2012)
    The article lists many drugs that treat high blood pressure but can also increase the risk of gout. If you have gout, ask your doctor whether your dose of any of these drugs could be reduced or whether you should switch to a medication with a lower gout risk. However, hypertension control is of utmost importance.
  • Corticosteroid Drug Interactions [hide all summaries]
    (November 2010)
    This article discusses 36 drugs that, when used by people also using a corticosteroid, can either cause toxic interactions with the steroid or decrease the steroid's effectiveness.
  • Drug-Induced Parkinsonism [hide all summaries]
    (October 2010)
    A study discovered that more than 1 out of every 10 people who went to a Parkinson’s disease center was found to have drug-induced Parkinsonism. These people were misdiagnosed as having the more common illness, Parkinson’s disease, which is irreversible and has unknown causes.
  • The Dangers of Combining Sleeping Pills With Other Medication [hide all summaries]
    (September 2010)
    The article list 34 other medications that can harmfully interact with sleeping pills, increasing their sedative properties and causing excessive sedation. Excessive sedation at night could increase the risk of falls, should the person get up in the night for some reason. Moreover, excessive sedation causing respiratory depression could be dangerous for people with certain disorders, such as lung disease.
  • Interactions With Cancer Drug Vincristine (ONCOVIN) [hide all summaries]
    (August 2010)
    The article lists 34 prescription drugs that can have harmful interactions with vincristine. Recognizing signs of toxicity from vincristine early, as described in the article, is urgent because most of the side effects are reversible when the interacting drug is stopped and the patient receives corrective treatment.
  • Oral Drugs for Diabetes: Avoiding Hypoglycemia [hide all summaries]
    (May 2010)
    After explaining the symptoms of low blood sugar (hypoglycemia) the article lists 42 prescription drugs that can interact with one or more diabetes drugs to increase the chance of hypoglycemia.
  • Aripiprazole (ABILIFY) Drug Interactions [hide all summaries]
    (April 2010)
    The article lists 53 drugs that can interact with the psychiatric drug ABILIFY to either increase the amount in the body, which can lead to toxicity, or decrease the amount rendering the drug less effective.
  • Digoxin Drug Interactions [hide all summaries]
    (March 2010)
    The article lists 35 different interacting drugs that can either increase blood levels of digoxin, leading to the serious problem of digitalis toxicity or decrease blood levels, causing the drug to be less effective.
  • Quetiapine (SEROQUEL) Interactions With Other Drugs [hide all summaries]
    (February 2010)
    Quetiapine (SEROQUEL) can interact with 26 different drugs, increasing its blood levels and causing dangerous side effects such as slowed breathing, dizziness and fainting. The article also lists 10 other interacting drugs that can result in lower blood levels, rendering the drug less effective.
  • Oxycodone: Be Careful What You Take With It [hide all summaries]
    (September 2009)
    The article lists 24 drugs that can increase the toxicity of oxycodone if taken together with the drug and 11 other drugs that can weaken its effectiveness as a painkiller if they are simutaneously used.
  • Muscle Damage from Interactions Between Statins and Other Commonly Prescribed Drugs [hide all summaries]
    (July 2009)
    The article lists 38 prescription drugs that can harmfully interact with statin drugs. The article also advises that No matter what statin you are taking and regardless of any interacting drugs, you should notify your prescriber immediately if you develop muscle pain, weakness or a darkening of your urine. .
  • Alpha-Blockers for Prostate Enlargement: Some Important Drug Interactions [hide all summaries]
    (June 2009)
    Taking alpha-blockers in combination with drugs for erectile dysfunction and with other drugs can cause dizziness and fainting. In this article we will discuss alfuzosin (UROXATRAL), doxazosin (CARDURA), tamsulosin (FLOMAX) and terazosin (HYTRIN) and drugs with which they can have harmful interactions.
  • Colchicine Interactions with Other Drugs Can Be Life-Threatening [hide all summaries]
    (December 2008)
    This article lists 27 drugs that can have life-threatening interactions with the widely-used gout drug, colchicine, resulting in dangerously elevated levels of colchicine. Too much colchicine in the body leads to toxicity such as fever, vomiting, diarrhea, abdominal pain and muscle pains. Even worse, it can impair the bone marrow’s ability to make red and white blood cells, causing severe anemia and dangerously low numbers of white blood cells. When the number of white blood cells is reduced, your body may have difficulty fighting infections. Most people who have died from colchicine toxicity have had bone marrow toxicity or had preexisting kidney problems. Every patient on colchicine — whether on other drugs or not — should be alert for evidence of colchicine toxicity as described above.
  • Calcium Channel Blocker Drug Interactions [hide all summaries]
    (May 2008)
    This article lists more than 60 prescription drugs that can interact with calcium channel blocking drugs such as amlodipine (NORVASC),diltiazem (CARDIZEM, DILACOR XR TIAZAC)or nifedipine (PROCARDIA)to either cause toxicity or to lessen the effectiveness of the calcium channel blocking drugs. Included in the lists are a number of drugs that we list in Worst Pills, Best Pills as DO NOT USE or LIMITED USE drugs. The article also explains the different kinds of toxicity that can ensue from these interactions.
  • Grapefruit Juice and Prescription Drugs: Some Dangerous Interactions [hide all summaries]
    (February 2004)
    The January 5th issue of the Medical Letter, a widely respected source of independent information about pharmaceuticals and dietary supplements, has a review of the increasingly researched problem of the interaction between grapefruit juice and many prescription and over-the-counter drugs. Like most interactions between chemicals in the body, this one involves the impairment, by grapefruit juice, of the body’s ability to metabolize many drugs, leading to higher than expected — and sometimes dangerous — levels of these drugs.This article lists the drugs.
  • Drug-Induced Taste Disorders [hide all summaries]
    (September 2003)
    DO NOT stop taking any of the drugs listed in the table without first consulting your physician. You should report any alteration in your sense of taste to your physician if you are taking a drug.
  • Review of Adverse Effects and Contraindications of Various Dietary Supplements Used for Weight Loss [hide all summaries]
    (December 2002)
    Ephedra, or ma huang, the natural form of the stimulant ephedrine, the most infamous and dangerous drug found in dietary supplements sold for weight loss, is at last beginning to receive the negative notoriety it deserves. Ephedra causes heart attacks and strokes because of its ability to raise blood pressure and heart rate. Article discusses the risk of other dietary supplements.
  • Drug Induced Psychiatric Symptoms [hide all summaries]
    (October 2002)
    This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.
  • Grapefruit Juice and Drug Interactions [hide all summaries]
    (June 2002)
    Grapefruit juice can interact with a number of therapeutically important drugs that could lead to the possibility of toxicity. These drugs are listed in the article.
  • Older Adults Not Getting the Most Effective Drugs For High Blood Pressure [hide all summaries]
    (January 2001)
    “You, or at least many of your colleagues, have failed to provide optimal care to your patients with high blood pressure.” This stinging critique of physician prescribing practices starts off an editorial in the Journal of General Internal Medicine for October 2000 that commented on a Harvard Medical School study of high blood pressure in older adults that appeared in the same issue.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion
  • [hide all summaries]
    This prescribing continues in the absence of evidence that these drugs [calcium channel blockers] prevent heart attack, heart failure, strokes or death and in the face of mounting evidence of their hazards. The FDA should also require patient package inserts for all calcium channel blockers.

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