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ibuprofen (ADVIL, CHILDREN’S ELIXSURE, IBU-TAB, IBU-TAB 200, IBUPROHM, MEDIPREN, MIDOL LIQUID GELS, MOTRIN, MOTRIN IB, NUPRIN, PROFEN, TAB-PROFEN)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
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Disease and Drug Family Information

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Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Drugs That Cause Sun-Related Skin Reactions [hide all summaries]
    (July 2016)
    Summer is a terrific time for healthy outdoor activities, such as walking, hiking, biking and swim¬ming. But for an unlucky few, certain medications can lead to adverse skin reactions following exposure to the sun. Find out whether you are at risk and how to protect yourself.
  • Drug-Induced Hair Loss [hide all summaries]
    (July 2016)
    For most people with hair loss, the condition usually is age-related or due to the genes they inherited from their parents. But for some patients, the cause of the problem can be found in the medicine cabinet. Learn about some commonly used medications that can cause hair loss.
  • Important Questions About Shingles [hide all summaries]
    (June 2016)
    Shingles is a very common disease caused by the chicken (herpes zoster) virus. Elderly adults are particularly vulnerable to developing this painful and sometimes debilitating condition. Learn the facts about shingles and how you can lower your risk of developing it.
  • Drugs That Cause Hearing Problems [hide all summaries]
    (November 2015)
    For most people with hearing loss, the condition likely is age-related or due to long-term exposure to loud noise. But for some patients, the cause of the problem can be found in the medicine cabinet. Learn about some commonly used medications that can cause hearing disorders.
  • FDA Bolsters Warnings About Heart Attack, Stroke Risks for Commonly Used Pain Drugs [hide all summaries]
    (September 2015)
    Worst Pills, Best Pills News editor Dr. Michael Carome discusses the FDA’s recent safety alert announcing that the agency is strengthening existing warnings in the product labels for all non-aspirin nonsteroidal anti-inflammatory drugs about increased risk of heart attack and stroke.
  • New Study Reveals Many Patients at Risk for Dangerous Alcohol-Drug Interactions [hide all summaries]
    (July 2015)
    Recent research revealed that many patients consume alcohol while using drugs that may can cause dangerous side effects when combined with alcohol. Read this article to learn about the many ways alcohol can adversely interact with prescription and over-the-counter medications.
  • Eight Treatments Commonly Used for Osteoarthritis Pain [hide all summaries]
    (July 2015)
    Patients with osteoarthritis have many treatment options. Find out which ones are safest for relieving osteoarthritis pain.
  • Hypertension Drugs Plus NSAIDs May Injure Kidneys [hide all summaries]
    (April 2013)
    Recent evidence points to increased acute kidney injury associated with combining nonsteroidal anti-inflammatory drugs (NSAIDs) with two antihypertensive drugs: a diuretic plus either an angiotensin-converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB). Find out the names of these drugs. This is especially important for patients with hypertension, diabetes, congestive heart failure or chronic kidney disease, because such patients are routinely treated with diuretics, ACE inhibitors and ARBs.
  • Interactions Between Methotrexate (TREXALL) and Proton Pump Inhibitors (PPIs) and Many Other Drugs [hide all summaries]
    (January 2011)
    This article discusses the dangerous interactions that can occur when using methotrexate (TREXALL) with certain other drugs. See our list of 27 drugs you should never take with methotrexate.
  • Preserving Bones with Bisphosphonates: Should You Avoid NSAIDs? [hide all summaries]
    (July 2010)
    It appears likely that patients who take bisphosphonates (such as FOSAMAX) and NSAIDs at the same time have an increased risk of gastrointestinal ulcers as opposed to taking either drug alone. The article reviews the studies demonstrating this and offers some practical advice on what the cautious drug user should do.
  • Risk of Serious Gastrointestinal Bleeding With Newer Antidepressant Drugs [hide all summaries]
    (April 2010)
    This article discusses the greatly increased risk of bleeding with some widely-used antidepressant drugs and provides information that the FDA has not yet required be included in the patient Medication Guides for these drugs.
  • Lithium Toxicity Due to Drug Interactions [hide all summaries]
    (January 2010)
    This article lists a large number of drugs, used to treat high blood pressure and other carediovascular disease, that can interact harmfully with lithium (ESKALITH; LITHOBID; LITHONATE;generic lithium carbonate), drugs used to treat bipolar (manic/depressive) disorder. This may result in a dangerous condition known as lithium toxicity because these drugs stop the body from getting rid of lithium and lithium blood levels are increased; in severe cases, this can cause seizures, coma and even death. The article also lists other symptoms of lithium toxicity.
  • Nonsteroidal Anti-Inflammatory Drugs Can Make Blood Pressure Hard to Control [hide all summaries]
    (February 2009)
    Twenty different NSAIDS (nonsteroidal antiinflammatory drugs) are listed in this article that can adversely affect your blood pressure control. The article discusses the way in which this happens and what you can do about it.
  • Update on Drugs that Can Cause High Blood Potassium [hide all summaries]
    (December 2008)
    This article lists 68 drugs that can cause high blood potassium (hyperkalemia) that can result in nausea, fatigue, muscle weakness or tingling sensations, as well as heart abnormalities (showing up as an abnormal electrocardiogram). In some cases it can be fatal. If you are taking any of these drugs, be especially careful if you have diabetes or kidney disease. If so, you are at increased risk, and your doctor will have to weigh the risk of giving you these drugs. Also, the older you are, the more likely you are to develop hyperkalemia. Also, make sure you are receiving appropriate laboratory monitoring.
  • Ibuprofen Can Reduce Aspirin’s Protective Effect Against Heart Attacks and Strokes [hide all summaries]
    (March 2008)
    This article explains the dangers of using ibuprofen (MOTRIN, ADVIL) because it interferes with the protective effect of low-dose aspirin to prevent blood clots and protect against heart attacks or strokes. Find out how these two widely-used therapies have a harmful interaction and what you should do.
  • Drug Induced Psychiatric Symptoms [hide all summaries]
    (October 2002)
    This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.
  • Comparative Gastrointestinal (GI) Toxicity of Six Nonsteroidal Anti-inflammatory Drugs (NSAIDs) [hide all summaries]
    (August 2002)
    The British equivalent of our Food and Drug Administration (FDA), in the April 2002 issue of its newsletter Current Problems in Pharmacovigilance, published a ranking of the relative gastrointestinal (GI) toxicity of some of the widely used older nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs are commonly used for acute pain and the treatment of the symptoms of osteo- and rheumatoid arthritis.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion
  • [hide all summaries]
    Statement of Dr. Peter Lurie, Deputy Director of Public Citizen’s Health Research Group

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